KEGG   Bos taurus (cow): 281971
Entry
281971            CDS       T01008                                 
Symbol
PDE2A
Name
(RefSeq) cGMP-dependent 3',5'-cyclic phosphodiesterase isoform PDE2A1
  KO
K18283  cGMP-dependent 3',5'-cyclic phosphodiesterase [EC:3.1.4.17]
Organism
bta  Bos taurus (cow)
Pathway
bta00230  Purine metabolism
bta01100  Metabolic pathways
bta04022  cGMP-PKG signaling pathway
bta04740  Olfactory transduction
bta04925  Aldosterone synthesis and secretion
bta05032  Morphine addiction
Brite
KEGG Orthology (KO) [BR:bta00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    281971 (PDE2A)
 09130 Environmental Information Processing
  09132 Signal transduction
   04022 cGMP-PKG signaling pathway
    281971 (PDE2A)
 09150 Organismal Systems
  09152 Endocrine system
   04925 Aldosterone synthesis and secretion
    281971 (PDE2A)
  09157 Sensory system
   04740 Olfactory transduction
    281971 (PDE2A)
 09160 Human Diseases
  09165 Substance dependence
   05032 Morphine addiction
    281971 (PDE2A)
Enzymes [BR:bta01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.17  3',5'-cyclic-nucleotide phosphodiesterase
     281971 (PDE2A)
SSDB
Motif
Pfam: PDEase_I GAF GAF_2 GAF_3 MIOS_a-sol
Other DBs
NCBI-GeneID: 281971
NCBI-ProteinID: NP_001243202
BGD-bta: BT26532
Ensembl: ENSBTAG00000008419
VGNC: 32674
UniProt: P14099
Structure
Position
15:complement(52131844..52229751)
AA seq 921 aa
MRRQPAASRDLFAQEPVPPGSGDGALQDALLSLGSVIDVAGLQQAVKEALSAVLPKVETV
YTYLLDGESRLVCEEPPHELPQEGKVREAVISRKRLGCNGLGPSDLPGKPLARLVAPLAP
DTQVLVIPLVDKEAGAVAAVILVHCGQLSDNEEWSLQAVEKHTLVALKRVQALQQRESSV
APEATQNPPEEAAGDQKGGVAYTNQDRKILQLCGELYDLDASSLQLKVLQYLQQETQASR
CCLLLVSEDNLQLSCKVIGDKVLEEEISFPLTTGRLGQVVEDKKSIQLKDLTSEDMQQLQ
SMLGCEVQAMLCVPVISRATDQVVALACAFNKLGGDLFTDQDEHVIQHCFHYTSTVLTST
LAFQKEQKLKCECQALLQVAKNLFTHLDDVSVLLQEIITEARNLSNAEICSVFLLDQNEL
VAKVFDGGVVEDESYEIRIPADQGIAGHVATTGQILNIPDAYAHPLFYRGVDDSTGFRTR
NILCFPIKNENQEVIGVAELVNKINGPWFSKFDEDLATAFSIYCGISIAHSLLYKKVNEA
QYRSHLANEMMMYHMKVSDDEYTKLLHDGIQPVAAIDSNFASFTYTPRSLPEDDTSMAIL
SMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNY
LEDMEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNT
HGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRTNKQHHSLLL
CLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQI
SFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIRGLPSNNSLDFLDEEY
EVPDLDGARAPINGCCSLDAE
NT seq 2766 nt   +upstreamnt  +downstreamnt
atgcgccgacagcctgcagccagccgggacctctttgcacaggagccagtgcccccaggg
agtggagacggcgcattgcaggatgctttgctgagcctgggctccgtcatcgacgttgca
ggcttgcaacaggctgtcaaggaggccctgtcggctgtgcttcccaaagtggagacggtc
tacacctacctgctggatggggaatcccggctggtgtgtgaggagcccccccacgagctg
ccccaggaggggaaagtgcgagaggctgtgatctcccggaagcggctgggctgcaatgga
ctgggcccctcagacctgcctgggaagcccttggcaaggctggtggctccactggctcct
gacacccaagtgctggtcataccgctggtggacaaggaggccggggctgtggcagctgtc
atcttggtgcactgtggtcagctgagtgacaatgaggagtggagcctgcaagctgtggag
aagcataccctggtggccctgaaaagggtgcaggccttgcagcagcgcgagtccagcgtg
gccccggaagcgacccagaatcctccggaggaggcagcgggagaccagaagggtggggtc
gcatacacaaaccaagaccgaaagatcctgcagctttgcggggagctctacgacctggat
gcatcttccctgcagctcaaagtcctccaatatctgcaacaggagacccaggcatcccgc
tgctgcctgctgctggtatccgaggacaatcttcagctctcctgcaaggtcattggagat
aaagtactggaggaagagatcagctttccgttgaccacaggacgcctgggccaagtggtg
gaagacaagaagtctatccagctgaaagatctcacctccgaggatatgcaacagctgcaa
agcatgttgggctgtgaggtgcaggccatgctctgtgtccctgtcatcagccgggccact
gaccaggtcgtggccctggcctgtgccttcaacaagctcggaggagacttgttcacagac
caggacgagcacgtgatccagcactgcttccactacaccagcacagtgctcaccagcacc
ctggccttccagaaggagcagaagctcaagtgtgagtgccaggctcttctccaagtggcg
aagaacctcttcactcatctggatgacgtctccgtgctgctccaggagatcatcacagag
gccaggaacctcagcaatgctgagatctgctctgtgttcctgctggatcagaacgagctg
gtggccaaggtgttcgatgggggtgtggtggaagatgagagctatgagatccgcattccc
gctgaccagggcatcgcgggtcatgtggcgaccaccggccagatcctaaacatcccagat
gcttacgcacatccgcttttctaccgaggcgtggacgacagcaccggcttccggacgcgc
aacatcctctgcttccccatcaagaacgagaaccaggaggtcatcggtgtggccgagctg
gtgaacaagatcaatggaccatggttcagcaagtttgatgaagacctggctacagccttc
tccatctactgtggcatcagcattgcccattccctcctatacaagaaagtgaatgaggcg
cagtatcgcagccaccttgccaatgagatgatgatgtaccacatgaaggtctctgatgac
gagtacaccaaacttctccatgacgggatccagcctgtggctgccatcgactccaacttt
gccagtttcacatacactcctcgctctctgcccgaggatgacacttccatggccatcctg
agcatgctgcaggacatgaatttcatcaataactacaaaattgactgcccgacactggcc
cggttctgtttgatggtgaagaagggctaccgggatcccccctaccacaactggatgcac
gccttttctgtctcccacttctgctacctgctctacaagaacctggagctcaccaactac
ctcgaggacatggagatctttgccttgtttatttcctgcatgtgtcacgacctggaccac
agaggcacaaacaactccttccaggtggcctcgaaatctgtgctggccgcgctctacagc
tcggaaggctctgtcatggagaggcaccacttcgctcaggccattgccatcctcaacacc
cacggctgcaacatctttgaccacttctcccggaaggattatcagcgcatgttggacctg
atgcgggacatcatcttggccacagatctggcccaccacctccgcatcttcaaggacctc
caaaagatggccgaagtgggctatgatcgaaccaacaagcagcaccacagcctccttctc
tgcctccttatgacctcctgtgacctctctgaccagaccaagggctggaagaccacgagg
aagatcgcggagctgatctacaaagagttcttctcccagggagacttggagaaggccatg
ggcaacaggccgatggagatgatggaccgtgagaaggcctacatccccgagctgcagatc
agcttcatggagcacatcgcaatgcccatctacaagctgctgcaagacctgttccccaag
gcggccgagttgtacgaacgcgtggcctctaatcgtgagcactggaccaaggtgtcacac
aagttcaccatccgaggcctcccgagcaacaactcgttggacttcctggacgaggagtat
gaggtgcctgacctggatggcgctagggctcccatcaatggctgttgcagccttgatgct
gagtga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (6)   
   KEGG PATHWAY (6)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (17)   
   KEGG ORTHOLOGY (1)   
   RefGene (10)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   BGD-BTA (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (7)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (5)   
DNA sequence (13)   
   RefSeq(nuc) (5)   
   GenBank (4)   
   EMBL (4)   
3D Structure (2)   
   PDB (2)   
Protein domain (5)   
   Pfam (5)   
All databases (61)   

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